Gel Filtration Resins

Gel filtration is a chromatographic method that realizes separation according to the difference in size and shape of biomolecules. The inside of gel filtration chromatography resin is a porous mesh structure, and the substances with too large size can not enter the inside of the resin, and go out of the outer water volume with the mobile phase, with a short retention time; small molecules can enter the inside of the resin, and the smaller the molecular weight is, the longer the retention time is in the inside of the resin, so that the substances flow out of the column according to the molecule size in succession, and the purpose of separation is achieved. The key to selecting gel filtration resin is to choose the appropriate pore size of the chromatography resin according to the molecular weight of the separated substances.