Ion Exchange Resins

Ion exchange chromatography (IEX) is a very effective method for the separation and purification of biomolecules, which mainly relies on the interaction between positive and negative charges, and utilizes the differences in the nature and amount of charges carried by different biomolecules under specific conditions to carry out the separation, and it is characterized by high loading capacity, good resolution, controllable conditions, and easy to be amplified. It has been widely used in medicine, chemical industry, metallurgy, food and other fields.

Ion exchange media is composed of three parts:

1. crosslinked mesh framework, the framework has a porous, hydrophilic, good chemical stability;
2. fixed on the framework of the functional group, it is the charge group, determines the nature of the ion exchange chromatography media; and
3. the functional group of the ion with an opposite charge (can be called the balance of the ion), the ion can be reversible with the combination of the functional group.