TD-CM25 is a weak cation exchange medium formed by coupling carboxymethyl on cross-linked dextran microspheres. It retains the excellent hydrophilicity and pore structure of natural polysaccharide compounds, and has excellent compatibility and very low non-specific adsorption of biologically active molecules. TD-CM25 is prepared on the basis of TD-G25, which has an extremely high loading capacity for small molecules, and is well suited for the isolation and purification of substances such as antibiotics and natural products. This chromatography medium is not suitable for loading into fixed-bed chromatography columns because of the large change in column bed volume in different buffers.
Specifications:
| Product |
TD-CM25 |
| Appearance |
White or yellow powder |
| Functional Group |
Carboxymethyl |
| Particle Size Range |
Dry: 40–120 µm |
| Solubility Coefficient |
7 mL/g dry powder (PBS) |
| Ion Loading Capacity |
4000–5000 µmol/g dry powder |
| Max. Pressure Tolerance |
0.3 MPa |
| Chemical Stability |
Stable in common aqueous solutions: 8M urea, 6M guanidine hydrochloride, 30% isopropanol, 70% ethanol |
| Operating pH Range |
6–10 |
| pH Stability |
2–12 (operating), 2–13 (CIP) |
| Recommended Flow Rate |
60–150 cm/h |
