TK-Col 26/10 Plasmid Fine

TH-Plasmid Fine is a thiophilic affinity medium made by immobilizing the sulfur-containing compound 2-mercaptopyridine on fine-grained, highly rigid agarose, with optimized ligand density and suitable affinity for superhelical DNA, and fine-grained microspheres that can enhance the loading of superhelical DNA with higher molecular weight. Thiophilic affinity is based on the principle of separating and purifying biomolecules by utilizing the interaction between electron donors and electron acceptors, which is strengthened in high-salt environments and weakened in low-salt environments.

TK-Col 26/10 Plasmid Fine preloaded columns are ready-to-use affinity chromatography columns filled with TH-Plasmid Fine media in TK-EC 26/20 chromatography columns. This series of columns eliminates the hassle of loading the columns by the customer and the risk of poor column performance. This type of preloaded columns is widely used in laboratory process development, small amount preparation of samples, and is suitable for the separation and purification of biomolecules such as superhelical DNA.