Heparin series is a race-specific affinity chromatography medium made by covalently coupling heparin to high cross-linking agarose. It is widely used for the separation and purification of various biomolecules, especially enzymes, including antithrombin III, thrombin-like enzymes, human coagulation factors IX, XI, VIII, lipoprotein lipase, collagenase, DNA polymerase and so on. It can also combine with human interleukin, human prostate growth factor, recombinant human vascular endothelial growth factor, chondrocyte growth factor, basic fibroblast growth factor, recombinant human acidic fibroblast growth factor, recombinant hepatocyte growth factor, recombinant murine heparin cofactor II, recombinant human platelet factor IV, recombinant endothelial inhibitor, recombinant human keratinocyte growth factor and other biomolecules. The medium is physically and chemically stable, the ligand is not easily dislodged, has a long service life, has a wide range of applications and is easily scaled up.
